NMDA Receptor Antagonists for Treatment of Depression
نویسندگان
چکیده
منابع مشابه
NMDA Receptor Antagonists for Treatment of Depression
Depression is a psychiatric disorder that affects millions of people worldwide. Individuals battling this disorder commonly experience high rates of relapse, persistent residual symptoms, functional impairment, and diminished well-being. Medications have important utility in stabilizing moods and daily functions of many individuals. However, only one third of patients had considerable improveme...
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Molecular and cellular studies have demonstrated opposing actions of stress and antidepressant treatment on the expression of neurotrophic factors, particularly brain-derived neurotrophic factor, in limbic structures of the brain. These changes in neurotrophic factor expression and function result in structural alterations, including regulation of neurogenesis, dendrite length and spine density...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2013
ISSN: 1424-8247
DOI: 10.3390/ph6040480